What Is Trifarotene (Aklief)?

Trifarotene seems to be a prescription retinoid cream often sold as Aklief. This medication appears to have been first approved in 2019. Reports indicate that it may be the only new retinoid approved in over twenty years. Most patients should only apply this medication once a day, often in the evening. Unfortunately, side effects seem to be quite common. They may include dry, itchy, and irritated skin. Patients may want to call their doctor if these side effects are persistent or bother them.

This medication seems to be a strong prescription for cystic acne treatment. However, patients may want to try an over-the-counter retinol cream first.