Causes Of Calcinosis Cutis

Subepidermal Nodules

Subepidermal nodules are associated with iatrogenic calcification, a subtype of calcinosis cutis without a known direct cause. The subepidermal nodules, which form right underneath the skin, may appear anywhere on the body, including underneath the skin of the eyelids. They are usually small, hard and white. These nodules may be accompanied by familial nodules or scrotal nodules. Familial nodules are more common in young individuals. All of these nodules are typically painless, but they can be aesthetically unpleasant or get in the way. They are sometimes surgically removed, and the surgery has few complications. However, the nodules can and often do recur.

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Medical Procedures Accidentally Leading To Calcium Salt Deposits

Iatrogenic calcification can be caused by medical procedures accidentally leading to calcium salt deposits. This sometimes happens to newborn babies when they get blood drawn from their heels. Iatrogenic calcification can also be caused by a variety of medical procedures involving calcium compounds. For example, when a patient gets an electroencephalograph, a calcium chloride paste is used on the electrodes. Having this paste on the skin for too long can cause calcium deposits to form. When individuals are treated for tuberculosis, they are given calcium solutions in an intravenous line. This procedure can lead to calcinosis cutis when too much calcium gets into the bloodstream.

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