Causes Of Calcinosis Cutis

Subepidermal Nodules

Subepidermal nodules are associated with iatrogenic calcification, a subtype of calcinosis cutis without a known direct cause. The subepidermal nodules, which form right underneath the skin, may appear anywhere on the body, including underneath the skin of the eyelids. They are usually small, hard and white. These nodules may be accompanied by familial nodules or scrotal nodules. Familial nodules are more common in young individuals. All of these nodules are typically painless, but they can be aesthetically unpleasant or get in the way. They are sometimes surgically removed, and the surgery has few complications. However, the nodules can and often do recur.

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