Clinical Presentation Of Type 1 Glycogen Storage Disease

Lactic Acidosis

Lactic acidosis is an accumulation of lactic acid in the body, and this symptom generally appears during infancy for individuals with type 1 glycogen storage disease. Patients experiencing lactic acidosis may have a decreased appetite, and they might develop muscle pain or cramps as well. Abdominal pain, fatigue, drowsiness, and weakness are frequently observed. In many cases, an accumulation of lactic acid is considered a medical emergency, and the patient should go to an emergency room for proper treatment. The standard course of treatment for excess lactic acid is to administer an intravenous infusion of sodium bicarbonate. Peritoneal dialysis with bicarbonate-based dialysate might be recommended as well.

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