Common Symptoms Of Mastocytosis

Nausea And Vomiting

Mast cells are responsible for causing symptoms in an individual's gastrointestinal system. These cells are critical immune system cells produced by the bone marrow that attack pathogens and release substances to eliminate any threat to the body. Mastocytosis patients experience higher levels of mast cells in their bodies than healthy individuals. Mast cells that detect an allergen release histamine, which causes swelling and redness of the affected area, producing inflammation. An individual who experiences inflammation of the nerves near the stomach and other digestive structures can experience nausea and vomiting as a result of the activation of the nausea center in the brain. Histamine is known to increase the production of gastric acid by the stomach, which can also cause nausea. Mast cell infiltration of the blood and digestive tract can result in hematological abnormalities. Some hematological abnormalities can make the patient prone to bleeding in their stomach and other parts of the gastrointestinal tract. Blood in the digestive tract serves as an irritant, and its presence can induce nausea and vomiting.

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