What Are The Complications Of Tuberous Sclerosis?

Excess Fluid Around And In The Brain

There are a number of different tumors that can occur in tuberous sclerosis. In around five to fifteen percent of individuals, tumors called subependymal giant cell astrocytomas (SEGAs) develop. These tumors can block certain brain functions and may lead to hydrocephalus when they block cerebrospinal fluid from flowing properly in the brain. Hydrocephalus occurs when excess amounts of cerebrospinal fluid accumulate around and inside the brain. When this fluid accumulates in the skull, it leads to abnormal pressure against the brain. Symptoms vary depending on the severity, but patients commonly experience behavioral changes, irritability, vomiting, nausea, and headaches. Other brain tumors can also lead to hydrocephalus, but not with the same frequency as subependymal giant cell astrocytomas.

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