Symptoms Of Selective IgA Deficiency And Related Conditions

Lupus

Selective IgA deficiency patients may also have an autoimmune disorder referred to as systemic lupus erythematosus, which has adverse effects on many organ systems of the body. Numerous types of autoantibodies are created in the body of an individual who has systemic lupus erythematosus against nuclear antigens deposited in multiple organs, including the kidneys, joints, and skin. The main method of treatment used for systemic lupus erythematosus patients is medications that suppress the immune system.

Systemic lupus erythematosus typically manifests following an infection that has triggered its characteristic symptoms. Those affected by selective IgA deficiency are included in the population of individuals who experience frequent infections because they are missing a critical component of their immune system. Because infection is one of the most prevalent causes of systemic lupus erythematosus, individuals who develop infections more frequently than others are at a greater risk of developing this autoimmune disease.