Warning Signs Of Marburg Hemorrhagic Fever
Headaches

The headaches that occur with Marburg hemorrhagic fever are severe, and they appear within the first five days of the illness. These headaches are largely unrelenting; rather than being intermittent, they tend to become progressively more intense. Patients with a severe headache may develop sensitivity to light, sound, and certain odors, and they may also experience blurry vision and other vision changes. For example, many patients with this illness develop red eyes. The pain from a severe headache often affects the entire head, and it can also shift from one side of the head to the other. Patients generally describe the pain as throbbing or pounding. Some individuals with these headaches may develop dizziness, and sensations of feeling very hot or very cold have been reported. As the headache worsens, patients may see flashing lights or dots in their visual field; this is known as an aura. Hospital treatment with intravenous pain relievers may help to reduce some of the pain from severe headaches.
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Maculopapular Rash

Patients entering the second phase of Marburg hemorrhagic fever may develop a maculopapular rash. This type of rash normally presents between days five to ten of the infection. Maculopapular rashes are made up of both flat and raised bumps that are normally red, and itching is typically present. For patients with Marburg hemorrhagic fever, the rash is generally concentrated around the trunk, including the back, chest, and stomach areas. At this stage, patients may develop chest pain, a cough, and a sore throat along with the rash, and they may begin to have signs of bruising on the skin. While maculopapular rashes are commonly treated with topical creams and oral medications, these treatments are unlikely to work for patients with Marburg hemorrhagic fever. However, hospital treatment may include the use of ointments that reduce itch to keep the patient comfortable.
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