Guide To The Causes Of Conn's Syndrome

Fluid Loss

An individual who has chronic fluid loss may develop Conn's syndrome as a result of their condition. One of the functions of the adrenal glands is to help the body when it is dehydrated. Dehydration occurs when less fluid is being consumed than is being excreted through the urine, sweat, feces, or vomit. Numerous factors can contribute to an individual's chronic dehydration or fluid loss, including infections, living conditions, malignancy, kidney problems, diarrhea, sweating too much, and urinating too much. When an individual loses too much fluid, the total blood volume decreases and causes a drop in blood pressure. Due to a decrease in blood pressure, blood does not make it to all of the tissues around the body. The kidneys filtering the blood receive signals from the brain indicating tissues are deprived of oxygen and there are low levels of sodium. Both processes tell the kidneys to produce more of a hormone called renin. Renin causes the activation of the hormone angiotensin, which then causes the adrenal glands to secrete more aldosterone. Chronic fluid loss triggers this cascade excessively, which can cause Conn's syndrome.

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