Guide To Treating Nephrogenic Systemic Fibrosis

Selected Medications

Nephrogenic systemic fibrosis patients may also be treated with selected medications that can ease symptoms and improve quality of life. For example, a medication called imatinib has shown some success in reducing the skin thickening and tightness that commonly occur with this disease. Another medication, pentoxifylline, may promote better circulation for patients by reducing blood viscosity (thickness). Sodium thiosulfate may be beneficial for some patients.

These medications are still under investigation, and patients using them should be aware of potential side effects. Imatinib can cause fever, rashes, nausea, vomiting, swelling, bleeding problems, bone pain, and muscle cramps. Patients taking pentoxifylline may develop flushing, blurry vision, bloating, upset stomach, and diarrhea. Potential side effects of sodium thiosulfate include tinnitus, joint pain, hallucinations, mental changes, and agitation. Patients and their caregivers should report any side effects to the prescribing physician as soon as possible.

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