How To Treat Primary Sclerosing Cholangitis

Liver Transplant

Some individuals with primary sclerosing cholangitis will eventually require a liver transplant. While measures can be taken in those with this condition to slow its progression and prevent complications, no known treatment will actually stop its progression. Eventually, injury and inflammation of the liver will occur because the bile has nowhere to go. With each subsequent episode of liver inflammation and injury, the body heals itself by developing scar tissue in the liver. Excessive liver scarring is known as cirrhosis, and this causes liver failure. Aside from liver failure, another circumstance that may necessitate a liver transplant in an individual with primary sclerosing cholangitis is frequent infections of the biliary system or bacterial cholangitis. In addition, primary sclerosing cholangitis patients are at a considerably higher risk of developing cancers of the liver, gallbladder, and bile ducts. If cancerous cells are found in any bile duct or liver tissues as a result of primary sclerosing cholangitis, a liver transplant may be warranted. When any symptoms of this condition become excessively debilitating and do not respond to other methods of treatment, a liver transplant may be considered.

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