What Is Trifarotene (Aklief)?

Potential Medication Interactions

Trifarotene seems to have many potential medication interactions. These interactions may increase the risk of side effects as well as their strength. Thus, patients may want to discuss their current medications and supplements with their doctor before starting this retinoid cream. They may also want to talk about their skincare products and the ingredients that they contain.

This medication seems to interact with eleven others. Examples appear to be isotretinoin, resorcinol, sulfur, and verteporfin. Ingredients such as salicylic acid and benzoyl peroxide may also interact with trifarotene. Unfortunately, those two ingredients appear to be quite common in over-the-counter skincare products, especially those intended for acne patients.