Guide To The Most Common Antidepressants

Atypical Antidepressants

Atypical antidepressants include any antidepressants that work differently than SSRIs, SNRIs, MAOIs, and tricyclic antidepressants. Many types of atypical antidepressants work by increasing levels of dopamine and norepinephrine in the brain, and they are often used in the treatment of depression and anxiety. They are often considered in cases of treatment-resistant depression that has not responded to other antidepressants. In addition, doctors might choose to prescribe atypical antidepressants for patients trying to quit smoking, as the drugs have been shown to reduce nicotine cravings. Vortioxetine, trazodone, bupropion, and esketamine are some of the most commonly prescribed atypical antidepressants in use today. Patients who take these medications should be aware of potential side effects such as dry mouth, dizziness, constipation, diarrhea, and weight gain. Esketamine, a new nasal spray intended for use in patients with treatment-resistant depression, must be administered by a psychiatrist or a primary care doctor, and bupropion should not be used by patients who have a history of seizures or eating disorders. Patients should check-in regularly with their healthcare team during treatment with atypical antidepressants. If troublesome side effects occur, it may be possible to switch to another medication in the same drug category.