Guide To The Side Effects Of Naproxen

Nausea And Vomiting

Nausea is not precisely a painful sensation but can be debilitating and very uncomfortable. Naproxen can cause nausea when it produces irritation in the tissues that line an individual's digestive tract. Mechanoreceptors and chemoreceptors send signals to the affected individual's brainstem when irritation is detected in the digestive lumen. The signals trigger several structures such as the dorsal motor vagus nucleus, central pattern generator, and solitary tract nucleus. These structures induce a chain of effects that accompany nausea in an affected individual, such as stopping the muscles of the lower digestive tract and increasing the production of saliva. Vomiting may occur following the feeling of nausea in an affected individual. Another circumstance where nausea and vomiting occur with naproxen use is when an ulcer has formed and has begun bleeding into the stomach.

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Chest Pain

Naproxen can cause an individual's blood pressure to become elevated, and elevated blood pressure causes the heart to work harder and faster than it would otherwise. Naproxen is known to decrease the quantity of prostaglandins in an individual's body, which can result in issues with the healthy function of their kidneys. Kidney function problems tend to cause the individual to retain more fluids in their body tissues, which further contributes to their elevated blood pressure and the heavy workload on their heart. Over an extended duration, the affected individual's heart muscle may fail to keep up with the demand of their body. When the heart has become weak and tired from the effects of regular naproxen use over an extended duration, it cannot adequately pump oxygenated blood to all of the body tissues. The brain senses low oxygen concentrations in tissues and signals the lungs to work harder along with the heart. The increased burden on the lungs and heart can manifest as chest pain.

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