How Is Pityriasis Rubra Pilaris Treated?

Biologic Therapies

Though there have been limited studies regarding the treatment's effectiveness, some patients may benefit from biologic therapies. This isn't a mainstream treatment for pityriasis rubra pilaris, but it has shown promise. Studies regarding the direct effect of biologic drugs on pityriasis rubra pilaris are limited because of the disease's rarity. However, there has been research done regarding the effect on psoriasis, which presents with very similar symptoms. Biologics are protein-based drugs created from cultures of living cells in a laboratory. Rather than suppressing the entire immune system, biologics target only specific portions of the immune system. Different biologics target different aspects of the immune system based on whatever part is causing problems. The biologics for psoriasis block certain proteins and immune cells from developing, which play a major role in the development of psoriasis symptoms. Similar treatments could be used to block the development of pityriasis rubra pilaris symptoms without compromising the entire immune system.

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