How To Manage Cataplexy

Use Medication When Needed

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It's important for patients dealing with cataplexy to use medication when needed. Since cataplexy and narcolepsy are sleep disorders, patients probably won't be able to mitigate all the symptoms through simple sleep hygiene. After they've made normal sleep hygiene changes, medication can help them further manage cataplexy. The United States Food and Drug Administration (FDA) has approved doses of sodium oxybate between six and nine grams, which patients can take nightly for cataplexy. Sodium oxybate has been shown to reduce the intensity and frequency of cataplexy episodes. Possible side effects include nausea, headache, and dizziness. Some research indicates antidepressants like serotonin-noradrenaline reuptake inhibitors (SNRIs) can help manage cataplexy. Some patients have also shown results with antidepressants like desipramine, imipramine, and clomipramine. With that said, the evidence is varied and needs more research. Though some patients may benefit from these medications, others might not.

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